Take tapentadol 100mg by mouth as directed by your doctor. You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible).
The dosage is based on your medical condition and response to treatment. Do not increase your dose or use this drug more often or for longer than prescribed. Properly stop the medication when so directed. Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.
Suddenly stopping this medication may cause withdrawal, especially if you have used it for a long time or in high doses. To prevent withdrawal, your doctor may lower your dose slowly. Tell your doctor or pharmacist right away if you have any withdrawal symptoms such as restlessness, mental/mood changes (including anxiety, trouble sleeping, thoughts of suicide), watering eyes, runny nose, nausea, diarrhea, sweating, muscle aches, or sudden changes in behavior.
Tapentadol works by binding to opioid receptors in the brain and spinal cord, altering how the body perceives and responds to pain. It also inhibits the reuptake of norepinephrine, enhancing its pain-relieving effects.
The 100mg strength refers to the amount of tapentadol in each tablet. Dosage and frequency are determined by the severity of the pain, individual response, and the healthcare provider’s prescription. Doctors often start with a lower dose and adjust it as necessary.