Meperidine 50mg


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Shipped From :Within United States
Delivery Time :3-4 Business Days
Product Dosage :50mg
Brand Name :Demerol, Pethidine 
Generic Name : Meperidine
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Meperidine, commonly known by its brand name Demerol, is an opioid analgesic medication used to alleviate moderate to severe pain. As an opioid, it functions by binding to opioid receptors in the brain and altering the perception of pain signals. Meperidine is often prescribed for short-term pain relief due to its rapid onset of action.

Here’s further information on Meperidine:

  1. Comparative Effectiveness

    Meperidine is comparable to other opioid analgesics in its pain-relieving effects. However, it might have a shorter duration of action compared to some other opioids, necessitating more frequent dosing.

  2. Medical Administration

    Meperidine is available in various forms, including oral tablets, injections, and suppositories. The choice of administration depends on the severity of pain and the rapidity required for pain relief.

  3. Metabolism and Side Effects

    It is metabolized in the liver. It  has potential side effects similar to other opioids, including constipation, dizziness, drowsiness, nausea, and potential for respiratory depression. However, it’s associated with a higher risk of producing neurotoxic metabolites compared to other opioids, especially in high doses or prolonged use.

  4. Usage Considerations

    Due to the risk of its toxic metabolite accumulation, meperidine is less commonly prescribed compared to other opioids for chronic pain management. It’s often reserved for short-term pain relief, such as post-operative or labor pain, where its rapid onset of action can be beneficial.

  5. Caution and Monitoring 

    Healthcare providers closely monitor patients receiving meperidine, especially those with renal impairment, as the accumulation of toxic metabolites can lead to seizures and other serious neurological complications.

  6. Drug Interactions

    It may interact with various medications, including other opioids, certain antidepressants, and monoamine oxidase inhibitors (MAOIs), potentially leading to serotonin syndrome or other adverse reactions.

  7. Alternatives and Recommendations

    Given its limitations and potential risks, healthcare providers often consider alternative opioids or non-opioid pain management strategies before prescribing meperidine.

Its unique pharmacological properties and potential for toxic metabolite buildup require careful consideration and monitoring when used in clinical settings. Always adhere to the prescribed dosage and consult healthcare professionals for guidance and monitoring while using meperidine for pain relief.



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